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Generic Viagra

Sildenafil

 

Nature and use of the drug

Sildenafil citrate is a drug that is use to treat erectile dysfunction in men. The pharmaceutical company, Pfizer, is selling it under the name Viagra. The scientists at Pfizer originally formulated Viagra to treat certain cardiovascular system problems such as hypertension and angina pectoris. Testing of the drug for the original purpose turned to be futile. They are of insignificant help to the problems they were intended for. During the testing for its effect on angina pectoris cases it had been noted that Viagra could cause penile erection. Further experiments were performed until the drug gained FDA approval as treatment of erectile dysfunction. Pfizer stared marketing the product for treating erectile dysfunction later in the year 1998. The FDA approved Viagra to be the first prescription medicine for treating erectile dysfunction in tablet form. Later, Viagra had been noted to help patients suffering from a rare disease called pulmonary hypertension. It was also recorded to lower the frequency of Raynaud's phenomenon attack. It was also noted that the duration of each attack had been reduced into half.

How this medicine works

Viagra works by inhibiting the phosphodiesterase type 5 (PDE5). This PDE5 is responsible for lowering the amount of cyclic guanosine monophosphate (cGMP)in the muscles of the penile area. If PDE5 is inhibited, there will be enough cGMP in the muscles of the penile area. Enough cGMP will cause these muscles to relax and the inflow of blood will increase. This now will cause an erection. The effect of Viagra in the wilting of plants was also noted and widely used. It has been used to effectively prolong the freshness of cut flowers. A small portion of Viagra is dissolved into the water where the stems of the cut flowers are soaked. Experiments were performed and it was recorded that flowers stayed fresh for twice the length of time that it would without the help of Viagra.

Dosage and administration

Viagra pills are available in 25, 50 and 100 mg tablets. It is recommended that a user starts with a 50mg tablet and then increase or decrease the dosage depending on how the pill reacted to the person. Viagra should be taken in between 4 hours to 30 minutes before the sexual activity. It takes effect in as fast as 30 minutes. This is the only drug for treating erectile dysfunction that was known to cause multiple erections. But it is also the one with the shortest effect of only up to 4 hours. Viagra should be taken only once per day.

What to expect -- side effects

Many men taking Viagra have experienced flushing of the face. This is normal with this drug and will not cause you any harm. Other mild side effects that usually go away after a few times of taking the medicine are upset stomach and headache. If these side effects bother you, consult your doctor. A few men experiences less common side effects that scare them. These are temporary color blindness or trouble of knowing which is green and which is blue and erection that lasts more than is expected. Report these matters to your doctor right away to know what you should and should not do.

Precautions to take

Safety precautions are to be considered before taking Viagra. Talk to your physician and discuss with him your actual physical condition and tell him all the medicines that you are taking. This way, you will avoid all complications that may occur if it was mishandled. There are several substances that are contraindicated with Viagra. Also, there are some medical conditions where sexual intercourse is not allowed. In order to stay on the safe side, have a thorough discussion with a health expert.



 

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